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Erratum: Chest CT Findings in Cases from the Cruise Ship “Diamond Princess” with Coronavirus Disease 2019 (COVID-19)
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В первых двух ключевых точках из 104 проанализированных случаев 76 (73%) были бессимптомными, 41 (54%) имели пневмонические изменения на КТ. Другие 28 (27%) случаев были симптоматическими, 22 (79%) имели патологические результаты КТ. Бессимптомные случаи показали большее преобладание GGO над консолидацией (83%), в то время как симптоматические случаи были более склонны к преобладанию консолидации над GGO (41%).
Резюме, Материалы и методы. Это ретроспективное исследование включало 104 случая (средний возраст 62 года ± 16, диапазон 25-93) с подтверждением COVID-19 методом ОТ-ПЦР.
Результаты. Из 104 случаев 76 (73%) были бессимптомными, 41 (54%) имели помутнения легких на КТ. Другие 28 (27%) случаев были симптоматическими, 22 (79%) имели патологические результаты КТ. Симптоматические случаи показали непрозрачность легких и нарушения дыхательных путей на КТ чаще, чем бессимптомные случаи [непрозрачность легких; 22 (79%) против 41 (54%), нарушения дыхательных путей; 14 (50%) против 15 (20%)]. Бессимптомные случаи показали больше GGO по сравнению с консолидацией (83%), в то время как симптоматические случаи чаще показали консолидацию по сравнению с GGO (41%). Степень тяжести КТ была выше в симптоматических случаях, чем в бессимптомных случаях, особенно в нижних долях [симптоматические и бессимптомные случаи; правая нижняя доля: 2 ± 1 (0-4) против 1 ± 1 (0-4); левая нижняя доля: 2 ± 1 (0-4) против 1 ± 1 (0-3); общий балл: 7 ± 5 (1-17) против 4 ± 2 (1-11)].
In the first two Key Points, Of 104 cases analyzed, 76 (73%) were asymptomatic, 41 (54%) of which had pneumonic changes on CT. Other 28 (27%) cases were symptomatic, 22 (79%) of which had abnormal CT findings. Asymptomatic cases showed more GGO predominance over consolidation (83%), while symptomatic cases were more likely to show a consolidation predominance over GGO (41%).
Abstract, Materials and Methods, This retrospective study comprised 104 cases (mean age, 62 years ± 16, range 25-93) with COVID-19 confirmed with RT-PCR.
Abstract, Results, Of 104 cases, 76 (73%) were asymptomatic, 41 (54%) of which had lung opacities on CT. Other 28 (27%) cases were symptomatic, 22 (79%) of which had abnormal CT findings. Symptomatic cases showed lung opacities and airway abnormalities on CT more frequently than asymptomatic cases [lung opacity; 22 (79%) vs 41 (54%), airway abnormalities; 14 (50%) vs 15 (20%)]. Asymptomatic cases showed more GGO over consolidation (83%), while symptomatic cases more frequently showed consolidation over GGO (41%). The CT severity score was higher in symptomatic cases than asymptomatic cases, particularly in the lower lobes [symptomatic vs asymptomatic cases; right lower lobe: 2 ± 1 (0-4) vs 1 ± 1 (0-4); left lower lobe: 2 ± 1 (0-4) vs 1 ± 1 (0-3); total score: 7 ± 5 (1-17) vs 4 ± 2 (1-11)].
Results, under Clinical Findings, The study population comprised 104 cases (54 men, mean age, 60 years ± 17, range: 31-87; 50 women, 63 years ± 15, range: 25-93). Of these cases, 76 (73%) were asymptomatic and 28 (27%) cases were symptomatic. The most frequent symptoms on admission were cough (20 [19%] cases), fever (11 [11%] cases), and fatigue (10 [10%] cases).
Results, under Chest CT Findings, first paragraph, Abnormal lung opacities (GGO and/or consolidation) and airway abnormalities (bronchiectasis and/or bronchial wall thickening) were present in 63 (61%) and 29 (28%) of the whole cohort, respectively. Lung opacities on CT were found in 41 (54%) of 76 asymptomatic. Twenty-two (79%) of 28 symptomatic cases had abnormal CT findings consistent with viral pneumonia. Comparing the two groups, symptomatic cases showed lung parenchymal and airway abnormalities on CT more frequently than did asymptomatic cases [symptomatic vs asymptomatic, lung opacity: 22 (79%) vs 41 (54%), p=0.023; airway lesion: 14 (50%) vs 15 (20%), p=0.002].
Results, under Chest CT Findings, second paragraph, Of 41 asymptomatic cases with lung opacities on CT, 17 (41%) cases had pure GGO, 7 (17%) GGO with intra- and interlobular septal thickening without consolidation, and 17 (41%) GGO with consolidation. Of 22 symptomatic cases who had lung opacities on CT, 5 (23%) cases had pure GGO, 4 (18%) GGO with intra- and interlobular septal thickening and without consolidation and 13 (59%) GGO with consolidation. In terms of the predominance of the lung parenchymal findings, asymptomatic cases showed GGO predominance over consolidation, while symptomatic cases were more likely to show consolidation predominance over GGO [asymptomatic vs symptomatic cases; GGO predominance: 34 (83%) vs 13 (59%); consolidation predominance: 7 (17%) vs 9 (41%), p=0.038]. In terms of the number of lesions, asymptomatic cases had a single lesion in 9 (22%) and more than 2 in 32 (78%) cases, compared to symptomatic cases, who had a single lesion in 4 (18%) and more than 2 in 18 (82%) cases. In terms of the axial distribution, more than half of the cases in each group showed a peripheral dominant distribution [24 (59%) asymptomatic vs 11 (50%) symptomatic cases]. On the other hand, only asymptomatic cases [4 (10%) cases] showed a central dominant distribution with single or multiple rounded GGO in one or multiple lobes. Symptomatic cases were more likely to show a mixed distribution (coexisting peripheral and central distribution) than asymptomatic cases [11 (50%) symptomatic vs 13 (32%) asymptomatic cases]. In both groups, the lower lobes were the most frequently affected; left and right lower lobe involvement were present in 17 (77%) and 17 (77%) of symptomatic cases and in 29 (71%) and 29 (71%) of asymptomatic cases. In addition, more than 2 lung lobes were affected in more than 75% of cases and bilateral lungs in more than 80% in both clinical groups. The CT severity score was significantly higher in symptomatic cases than asymptomatic cases in the right and left lower lobes and overall lung [symptomatic vs asymptomatic cases; right lower lobe: 2 ± 1 (0-4) vs 1 ± 1 (0-4), p=0.048; left lower lobe: 2 ± 1 (0-4) vs 1 ± 1 (0-3), p=0.019; total lung score: 7 ± 5 (1-17) vs 4 ± 2 (1-11), p=0.025].